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Browse content Table of contents. Description The second edition of The Blood Group Antigen FactsBook provides key information relating to human red blood cell membrane components carrying blood group antigens, the molecular basis of the antigens, their serological characteristics, and the clinical significance of blood group antibodies. Key Features Over fully updated entries on blood group antigens, formatted on single pages for easy use Inclusion of RHAG blood group system and over twenty new antigens Basic science paired with clinical applications to give context to information Full-color illustrations, gene maps and charts Both traditional and ISBT-sanctioned naming conventions included.

Over fully updated entries on blood group antigens, formatted on single pages for easy use Inclusion of RHAG blood group system and over twenty new antigens Basic science paired with clinical applications to give context to information Full-color illustrations, gene maps and charts Both traditional and ISBT-sanctioned naming conventions included.

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The third edition of The Blood Group Antigen FactsBook has been completely revised, updated and expanded to cover all 33 blood group systems. Product details Format Paperback pages Dimensions x x Other books in this series. Add to basket. The Transporter Factsbook Jeffrey Griffith.

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(ebook) Blood Group Antigen FactsBook

The Chemokine Factsbook Krishna Vaddi. Review Text Praise for the first edition: "This compact paperback has quickly become the most valued and useful resource in my blood banking and immunohematology library However, it is highly readable and skimming its' tables and figures will be an enjoyable, painless way to update your information about blood group antigens. Once you start reading this unique compilation of facts and information about blood group antigens, you will not be able to stop until you read the last page.

Review quote Praise for the first edition: "This compact paperback has quickly become the most valued and useful resource in my blood banking and immunohematology library Terminology for blood group antigens and genes: Historical origins and guidelines in the new millennium.

The Blood Group Antigen Facts Book by Marion Reid, Christine Lomas-Francis | Waterstones

Section II is organized into four main parts: i the blood group systems; ii the blood group collections; iii the Series of Low-Incidence Antigens; and iv the Series of High-Incidence Antigens. For the systems, facts pertaining to the gene, carrier molecule, and antigens, and the clinical relevance of antibodies are given. For the collections, series of low-incidence antigens, and series of high-incidence antigens, facts pertaining to the antigens and antibodies are given. All are listed in ISBT numerical order. The format for the facts sheets displaying the data about the systems and the antigens is explained below; that for the collections and high-incidence antigens is similar.

2nd Edition

The Series of Low-Incidence Antigens are given in a table. Section III consists of facts in lists and tables where the information encompasses more than one antigen or blood group system. Other related information is also included. Both the ISBT system symbol and traditional name are used in the section headings. Information is provided under the following headings. The total number of antigens in the system is indicated. The antigens are listed under the headings: polymorphic in blue font ; high prevalence in red font ; and low prevalence in green font.

Table 2. If a number assigned to an antigen becomes inappropriate, the number becomes obsolete and is not reused; such antigens are noted with three small dots …. Both the traditional name and the ISBT symbol for the blood group system are given as headers. This section relates to the component on which the antigens in a blood group system are carried. Several blood group antigens occur naturally in soluble form in body fluids e.

If a naturally occurring soluble form of the carbohydrate antigen or carrier protein is available, it will be indicated in this section. Soluble forms of an antigen can be used for inhibition tests to confirm or eliminate antibody activity.


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If the soluble form of the antigen is to be used for inhibition studies, the substance must be obtained from a person who inherited the antigen of interest and be made isotonic. A soluble form of many antigens can be produced through recombinant technology. Some of the components carrying blood group antigens have been detected on other blood cells and tissues by use of various methods, including testing with polyclonal and monoclonal antibodies or by Northern blot analysis.

The Blood Group Antigen FactsBook

However, it cannot be assumed that detection of the carrier molecule equates with the expression of the RBC antigen s. Under the subheading Other blood cells, we refer to cells in the peripheral blood excluding RBCs because it goes without saying that RBCs express all the components carrying blood groups except in null phenotypes.

The chromosome number, arm [short p upper on diagrams ; long q lower on diagrams ], and band number are given. The name of the gene used is that recommended by the ISBT, with alternative names in parenthesis. If the presence of a blood group antigen is detected by serological means, the gene is named by the corresponding ISBT system symbol, an asterisk followed by the antigen number, in italics to indicate the specific allele, e.

The organization of the gene in terms of number of exons, kilobase pairs of gDNA, and an overview map are provided.


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The gene product name and alternatives is given. Key GenBank accession numbers and the Entrez gene number are given. Tables listing alleles encoding blood group variants, together with relevant information, are given. For updates, go to the ISBT website www. The accession number for the reference allele is indicated, and key nucleotide differences are noted for each allele.